The first research group of Professor Zhao Yuanjin, the State Key Laboratory of Bioelectronics, has developed a color changing "heart chip" that monitors the response of the heart to different drugs through the color changes of the chip, thus eliminating animal and clinical trials, providing a new platform for drug screening and research and development, which can be greatly reduced. The cost of new drug research and development.
Organ chip is one of the most popular modern tools in biological research, which is one of the most popular new tools in biological research, which is one of the most popular tools in biological research. It is important to support the development of innovative drugs in China and the progress of transformation medicine. Professor Zhao Yuanjin's team researchers combined a gel with a special optical structure with living cardiac myocytes. After the cell is set on the surface of a jelly like hydrogel, its contraction and relaxation can lead to a change in the shape of the gel film. With the change of crystal alignment in the gel, the interference effect between the reflected light will also change. Therefore, the pulsation of cardiac myocytes can be visualized by different colors, and then the heart reaction is monitored through the change of color of the chip, thus, the "heart chip" which has the function of microphysiologic visualization is constructed.
Discoloration "heart chip", developed by Professor Zhao Yuanjin, is the first time in the world and represents a major breakthrough in the key technology platform for innovative drug research and development in China. The results of the study were published in the world's principal journal Science robot in March 29th with the theme of "living structure color material", which is the first time Chinese scholars have completed their paper independently.